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research dossier

TRUDEAU INSTITUTE INC

SARANAC LAKE, NY · EIN 141401413 · Form 990 · FY2024 · NTEE H900 · Medical Research · Medium ($1M-$10M) · trudeauinstitute.org
revenue
$8.2M
expenses
$10.3M
net assets
$18.8M
employees
89
volunteers
20
program ratio
88%
mission · from form 990

SCIENTISTS AT TRUDEAU INSTITUTE FOCUS ON DEVELOPING AN IN-DEPTH UNDERSTANDING OF THE ROLE OF THE IMMUNE SYSTEM IN HEALTH AND DISEASE TO FACILITATE THE DEVELOPMENT OF THERAPEUTIC TREATMENTS AND FINDING CURES. THROUGH RIGOROUS EXPERIMENTATION, COMBINED WITH ADVANCED ANALYTIC AND SOFTWARE TOOLS, THESE EFFORTS LEAD PROGRESS TOWARDS STRENGTHENING OUR BODIES' ABILITIES TO COMBAT LIFE THREATENING INFECTIONS, INFLAMMATORY DISEASES, AND CANCER. DISCOVERIES ON THE INTRICATE WORKING OF THE IMMUNE SYSTEM APPLY TO A VAST ARRAY OF HUMAN AFFLICTIONS INCLUDING, BUT NOT LIMITED TO, TUBERCULOSIS, INFLUENZA, COVID-19, AND IMMUNE CELL-DRIVEN MALADIES.

profile · synthesized from sources

Trudeau Institute is a nonprofit biomedical research institute founded in 1884 in Saranac Lake, NY, focused on understanding the immune system's role in combating infectious diseases, cancer, and inflammatory conditions. The institute conducts fundamental and translational research on pathogens including tuberculosis, influenza, Zika, and SARS-CoV-2, with the goal of developing novel therapeutics, vaccines, and diagnostic tools. It also offers a semester-long Biomedical Research Scholars Program for undergraduate students.

named programs · 11 · from sources

What they call their work

Biomedical Research Scholars Program
Semester-long, 15-credit experiential learning program for undergraduates focusing on immunology, microbial pathogenesis, and vaccine development, including laboratory research and advanced coursework.
Computational Chemogenomics Program
Applies structural bioinformatics and chemoinformatics to identify novel small-molecule drug candidates targeting essential genes in pathogens like Mycobacterium tuberculosis.
Dengue & Zika Research Program
Uses genetically modified mouse and pregnancy models to study flavivirus immunogenicity and evaluate candidate vaccines and therapeutics for dengue and Zika viruses.
Flow Cytometry Core Facility (TIFCC)
Provides access to flow cytometry and cell sorting instrumentation, technical support, and data analysis services for internal and external researchers.
Histology/Imaging Core
Supports histology, immunohistochemistry, immunofluorescence, and advanced microscopy including confocal imaging with environmental control for live-cell studies.
Influenza Research Program
Develops universal influenza vaccine strategies targeting conserved viral proteins to provide broad protection against seasonal and pandemic strains.
Laboratory Animal Facilities
USDA-registered, AAALAC-accredited facility providing animal husbandry, breeding, biosecurity, and colony management for ABSL1-3 research models.
Mass Spectrometry Core Facility
Offers ultra-high performance liquid chromatography–quantitative time of flight mass spectrometry for sensitive detection and quantification of small molecules in drug discovery research.
Tuberculosis Research Program
Studies Mycobacterium tuberculosis persister cells and granuloma biology to identify novel therapeutic targets and shorten treatment duration for drug-sensitive and drug-resistant TB.
Vaccines, Adjuvants and Mucosal Immunity Program
Investigates adjuvanted vaccines and mucosal delivery methods to stimulate durable cellular and humoral immunity against pathogens including TB, influenza, Zika, and SARS-CoV-2.
Veterinary Services Core
Oversees animal health monitoring, quarantine, surgical support, and training for research staff working with animal models.
activities · 5 groups

What they do

  • Biomedical Research and Innovation 1 activity
    • Infectious disease research on tuberculosis, influenza, COVID-19, and emerging viruses
      Conducts specialized research to understand immune responses and develop therapeutic interventions for life-threatening infectious diseases including tuberculosis, influenza, Zika, SARS-CoV-2, and flaviviruses. Research includes genomic analysis, drug discovery, vaccine development, and preclinical modeling using genetically modified mice and advanced imaging techniques.
  • Student Housing and Residential Services 1 activity
    • On-campus housing and childcare services
      Operates 12 rental housing units and a daycare center on campus to support staff and visitors.
  • Research Facility Management 1 activity
    • Operation of high-containment research facilities and core scientific instrumentation
      Operates a 90,000 square foot research facility with BSL3 and ABSL3 containment spaces, advanced imaging systems (including confocal microscopy), flow cytometry platforms (BD LSR II, FACSCanto II, BD Influx), and mass spectrometry (UHPLC-QTOF) for drug discovery. Provides 24/7 access and technical support for trained researchers.
  • Medical Professional Education & Training 1 activity
    • Training and technical support for research staff and scholars
      Provides training and direct technical assistance in surgical procedures, laboratory techniques, flow cytometry, and imaging equipment use. Offers a semester-long Biomedical Research Scholars Program focused on immunology and vaccine design through hands-on laboratory experience.
  • Uncategorized 1 activity
    • Research animal care, colony management, and biospecimen coordination
      Provides comprehensive animal husbandry and colony management services for research models, including breeding programs, health and environmental monitoring, import/export quarantine, and biospecimen screening. Maintains ABSL1-3 housing with advanced containment systems and employs AALAS-certified technicians. Supports compliance with USDA, NYSDOH, and CDC standards.
financials · form 990 · fy2024
revenue
Total revenue$8.21M
Contributions & grants$675K8%
Program service revenue$6.35M77%
Investment income$840K10%
Other revenue$348K
expenses
Total expenses$10.30M
Program expenses88%
Admin / overhead10%
Fundraising2%
Salaries & benefits$5.51M
Grants paid out$0
Largest expense lineCompensation
balance sheet
Total assets$19.65M
Cash$389K
Investments$8.27M
Liabilities$900K
Net assets$18.75M
Liquid reserves10.1 mo
3 years on record · 2020–2024 · YoY revenue +15.5%
leadership · form 990 part vii · fy2024

Who runs it

paid leadership · 7
NameTitleHours/wkCompensation
WILLIAM REILEY PRESIDENT AND DIRECTOR 38 $220K
ALEX MAUE BUSINESS DEVELOPMENT/ COO 38 $169K
SHELTON BRADRICK PRINCIPAL INVESTIGATOR 38 $159K
TINA MOODY CAO, TREASURER - SECRETARY 38 $156K
BRIAN WEINRICK PRINCIPAL INVESTIGATOR 38 $131K
IN-JEONG KIM PRINCIPAL INVESTIGATOR 38 $130K
KRISTOFER FRIERS IT MANAGER 38 $118K
board members · 15
  • AIRLIE CAMERON LENNON MDMPH — TRUSTEE
  • ANDREW KENNEDY — TRUSTEE
  • BENJAMIN BREWSTER — TRUSTEE
  • BRUCE MCLANAHAN — TRUSTEE
  • DANIEL KARLIN — TRUSTEE
  • DANIEL LEFF — TRUSTEE
  • DANIEL PAPES — VICE CHAIR
  • HENRY SONDHEIMER — VICE CHAIR
  • JULIE NORTH — CHAIRPERSON
  • KENNETH BAYLES — TRUSTEE
  • KONRAD KIP TESTWUIDE — TRUSTEE
  • RAYMOND N JOHNSON PHD — TRUSTEE
  • STEVE ANDRZEJEWSKI — TRUSTEE
  • TIELMAN T VAN VLECK PHD — TRUSTEE
  • VINCENT A FISCHETTI PHD — TRUSTEE
relationships · 9

Who they work with

  • Agilent Partner — Supplies instrumentation (Agilent 6545 Q-TOF, 1290 Infinity II UHPLC) and software (MassHunter) for the Mass Spectrometry Core Facility.
  • American Association for Laboratory Animal Science Partner — Provides certification for Laboratory Animal Care Technicians employed at the Institute.
  • Centers for Disease Control and Prevention Government — Conducts regular inspections of the Laboratory Animal Facilities.
  • National Institutes of Health Government — Provides the Research Ethics curriculum for the Responsible Conduct of Research course.
  • New York State Department of Health Government — Conducts regular inspections of the Laboratory Animal Facilities.
  • Trudeau Research Network Network — Network expanded to jointly combat national and global infectious disease threats
  • United States Department of Agriculture Animal and Plant Health Inspection Service Government — Conducts regular inspections of the Laboratory Animal Facilities.
  • noncommercial vendors Partner — Coordinates importation and exportation of mice with noncommercial vendors.
  • other research facilities Partner — Coordinates importation and exportation of mice with other research facilities.
strategies · 5

How they approach the work

Named approaches extracted from this org’s sources. Where others share an approach, follow it to see the full set of orgs running it.

  • Adjuvant-Enhanced Mucosal Immunity
    methodology: adjuvant-enhanced_mucosal_immunity
    By administering vaccines at mucosal sites and using adjuvants to boost immune responses, the Institute generates tissue-resident T cells that act quickly at pathogen entry points, because localized immunity provides faster and more effective protection against infectious diseases.
  • Computational Drug Repurposing
    methodology: computational_drug_repurposing
    By computationally reanalyzing existing drug libraries, the Institute discovers new antimicrobial applications for well-characterized molecules, because this approach accelerates drug discovery by bypassing early safety testing and leveraging known pharmacological profiles.
  • Pandemic Preparedness Through Platform Science
    methodology: pandemic_preparedness_through_platform_science
    By leveraging established research platforms, the Institute can rapidly develop new therapeutics and vaccines in response to emerging pandemic threats, because platform-based science enables agile adaptation to novel pathogens without starting from scratch.
  • Pathogen-Biology-Driven Drug Discovery
    methodology: pathogen-biology-driven_drug_discovery
    By studying how pathogens like tuberculosis bacteria grow and survive in host environments, the Institute identifies novel therapeutic targets that improve and shorten treatment, because deep biological understanding of infection mechanisms reveals vulnerabilities that can be exploited for drug development.
  • Translational Science Partnerships
    methodology: translational_science_partnerships
    By combining specialized research capabilities with medical research universities and government agencies, the Institute accelerates the development of therapeutics and vaccines, because collaborative networks enhance scientific innovation and real-world application through shared expertise and resources.