named programs · 3 · from sources
What they call their work
Early Feasibility Studies
Assesses technical and regulatory feasibility of novel medical devices to de-risk development and accelerate time to market
Office of Regulatory & Quality Services
Provides expert guidance on FDA pathways, risk assessment, submission preparation, and quality compliance for medical device developers
i2R (idea to Reality) Center
Core innovation hub that translates medical device concepts into therapeutic and commercial successes through engineering, testing, and regulatory support
activities · 4 groups
What they do
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Biomedical Research and Innovation 4 activities
- Advancing research and clinical treatment in minimally-invasive vascular surgeryConducts and supports research, teaching, and clinical treatment focused on minimally-invasive surgery for global vascular disease, including the development and testing of novel medical devices and therapies.
- Designing and manufacturing anatomical models for medical device developmentDesigns, validates, and manufactures patient-specific 3D-printed anatomical models with tunable physical properties (e.g., compliance, puncture force) using 510(k)-cleared segmentation workflows and single or multiple patient scans. Models are used for simulation, testing, and regulatory support within a certified Quality Management System.
- Facilitating collaborative innovation in vascular medicineBrings together clinicians, researchers, engineers, and entrepreneurs through co-location with a university research institute and hospital to accelerate medical technology development. This includes immersive collaboration in a shared facility integrating innovation, training, and clinical feedback.
- Operating the Idea to Reality (i2R) Center for medical technology translationRuns the i2R Center to accelerate the development of life-saving vascular devices by shortening the timeline from concept to clinical implementation, including translating technologies into therapeutic and commercial applications.
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Medical Professional Education & Training 1 activity
- Delivering clinical training programs for healthcare and industry professionalsProvides clinical training programs for physicians, engineers, medical executives, and sales representatives in neuro, cardio, EP, and spine specialties. Programs include endovascular simulation, bioskills labs, cadaveric specimens, live surgical observation, and clinical needs identification using the Biodesign process. Hosted over 90 programs in 2021 and trained over 3,250 professionals in person since 2014, with thousands more trained virtually.
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Healthcare Workforce Training & Career Pathways 1 activity
- Providing experiential learning and workforce development programsOffers education and training programs for high school and college students, including a two-week program for Buffalo-area high school students, summer internships for college students in engineering and regulatory fields, and outreach to K–12 students through campus visits focused on vascular disease, 3D printing, and clinical simulation. Also hosts webinars and participates in science exhibitions.
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Advanced Surgical and Cardiac Care 1 activity
- Providing medical device development and testing servicesOffers vascular device testing, on-site prototyping, pre-clinical in vivo studies (GLP or non-GLP), ex vivo and cadaveric tissue testing, and engineering validation services to advance medical device innovation. Operates under ISO 13485:2016-certified quality systems.
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financials · form 990 · fy2024
revenue
Total revenue$12.45M
Contributions & grants$2.57M21%
Program service revenue$9.72M78%
Investment income$63K1%
Other revenue$93K
expenses
Total expenses$11.65M
Program expenses77%
Admin / overhead22%
Fundraising1%
Salaries & benefits$4.94M
Grants paid out$0
Largest expense lineCompensation
balance sheet
Total assets$7.40M
Cash$1.99M
Investments$479K
Liabilities$3.75M
Net assets$3.65M
Liquid reserves2.5 mo
4 years on record · 2020–2024 · YoY revenue -0.8%
leadership · form 990 part vii · fy2024
Who runs it
paid leadership · 7
| Name | Title | Hours/wk | Compensation |
|---|---|---|---|
| ADNAN H SIDDIQUI MD | CHIEF MEDICAL OFFICER & CEO | 40 | $606K |
| CARLOS PENA | CHIEF REGULATORY & QUALITY OFFICER | 40 | $375K |
| TIMOTHY KORN | CHIEF FINANCIAL OFFICER | 40 | $193K |
| ADAM SPARKS | DIRECTOR OF ENGINEERING | 40 | $184K |
| KARI ANASTASIA | DIRECTOR OF ENGINEERING | 40 | $170K |
| PAMELA MARCUCCI | VP OF PROGRAMS | 40 | $164K |
| DANIEL LAWRENCE | SENIOR PROGRAM MANAGER | 40 | $145K |
board members · 11
- BRUCE W MOSKOWITZ MD — DIRECTOR
- DANIEL J ZIMMER — TREASURER
- DONALD BOYD — DIRECTOR
- GERALD S LIPPES — DIRECTOR
- JEREMY M JACOBS — CHAIRMAN
- JEREMY M JACOBS JR — DIRECTOR
- MICHAEL MCCABE ESQ — ASSISTANT SECRETARY
- ROBERT T BRADY — DIRECTOR
- SATISH K TRIPATHI PHD — DIRECTOR
- THOMAS R BEECHER JR — SECRETARY
- WILLIAM G GISEL JR — DIRECTOR
relationships · 42
Who they work with
- Abbott Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Abiomed (Johnson & Johnson) Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Angiodynamics Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Apple Partner — Employer of former Jacobs Institute interns, indicating a talent development and workforce pipeline relationship.
- Boston Scientific Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Boston Scientific Partner — Employer of former Jacobs Institute interns, indicating a talent development and workforce pipeline relationship.
- Buffalo Niagara Medical Campus Partner — Hosts The Jacobs Institute on its campus, enabling integration within a medical and research hub.
- Cerenovus Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Congress of Neurological Surgeons Partner — Sponsors resident and fellow programs and labs at the Jacobs Institute.
- Congress of Neurological Surgeons Partner — Sponsors resident and fellow training programs and labs at The Jacobs Institute.
- Cook Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Edwards Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Empire State Development Funder — Endowing benefactor supporting the Jacobs Institute since its founding.
- Food and Drug Administration Government — Collaborates with the FDA to support regulatory submissions and engagement for medical device developers.
- Global Vascular Institute (GVI) Partner — Collaborates on clinical training programs, including live case observation and discussion with surgeons from GVI catheterization labs.
- Gore Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- IRRAS Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- ISO Government — Certified to ISO 13485:2016 for quality management in medical device and anatomical model development.
- ISO Government — Certified to ISO 13485:2016 for quality management in medical device development and testing.
- Integra Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- James H. Cummings Foundation, Inc. Funder — Foundation supporter of the Jacobs Institute.
- Kaleida Health Partner — Close partnership enabling access to and collaboration with physicians and researchers specializing in vascular disease.
- Kaleida Health Partner — Health system partner with which the Jacobs Institute is co-located, enabling integration between clinical care and innovation.
- Kaleida Health Partner — Strategic location adjacent to a state-of-the-art vascular hospital (Kaleida Health's Gates Vascular Institute) to enable clinical integration and real-time physician collaboration.
- Lippes Mathias Wexler Friedman LLP Funder — Foundation-level supporter of the Jacobs Institute.
- Medtronic Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- MicroVention Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- Mivi Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
- NSF Partner — Employer of former Jacobs Institute interns, indicating a talent development and workforce pipeline relationship.
- OpSens Partner — Collaborates with the Jacobs Institute on clinical training and immersion programs.
+ 12 more
strategies · 5
How they approach the work
Named approaches extracted from this org’s sources. Where others share an approach, follow it to see the full set of orgs running it.
- Collision-Based Innovation Ecosystemmethodology: collision_based_innovationBy intentionally creating interactions ("collisions") among physicians, engineers, entrepreneurs, and industry partners in a shared physical and intellectual environment, the organization accelerates medical innovation because cross-disciplinary exposure generates novel solutions that single-domain teams cannot achieve.
- Early Regulatory Engagement for Accelerated Market Entrymethodology: early_regulatory_engagementBy promoting early interaction with regulatory bodies like the FDA and integrating regulatory strategy into product development, the organization reduces risk and accelerates market entry because developers can align design and testing with regulatory requirements from the outset.
- Experiential Project-Based STEM Pathway Developmentmethodology: project-based-mentorshipBy engaging high school students in mentor-guided, project-based learning aligned with real organizational needs, the organization cultivates long-term STEM and medical career pathways because early, hands-on experience increases motivation, skill development, and professional identity formation.
- Integrated Clinical-Technical Translation Modelmethodology: integrated_clinical-technical_collaborationBy colocating clinical practice, engineering, and research with real-time feedback loops, the organization accelerates the development of medical technologies because clinical immersion ensures that device design is continuously informed by real-world use and patient needs.
- Patient-Centered, Anatomically-Driven Design and Testingmethodology: patient-centered_designBy using patient-specific anatomical data, 3D-printed models, and multisource imaging to drive device design and testing, the organization improves clinical relevance and device efficacy because models replicate real physiological and pathological conditions, enabling more accurate development and validation.