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NATIONAL CANCER CENTER INC

West Islip, NY · EIN 131919715 · Form 990 · FY2024 · NTEE G30Z · Voluntary Health Associations · Medium ($1M-$10M) · nationalcancercenter.org
revenue
$3.6M
expenses
$4.9M
net assets
$575K
employees
3
program ratio
46%
mission · from form 990

NATIONAL CANCER CENTER (NCC) FOUNDED BY DR. ERNEST AYRE IN 1953 AS A NON-PROFIT ORGANIZATION COMMITTED TO OVARIAN CANCER RESEARCH AND EDUCATION. NCC HAS EXPANDED ITS MISSION TO SUPPORT SEVERAL TYPES OF CANCER RESEARCH AND EDUCATION TO INCLUDE:BREAST CANCER RESEARCH CHILDRENS CANCER RESEARCH CHILDHOOD LEUKEMIA RESEARCH AGGRESSIVE CANCER RESEARCH PROSTATE CANCER RESEARCH

profile · synthesized from sources

NATIONAL CANCER CENTER INC (NCC), founded in 1953 by Dr. Ernest Ayre, is a nonprofit organization dedicated to advancing cancer research and public education. The organization funds post-doctoral research fellowships in areas including ovarian, breast, prostate, childhood, and aggressive cancers, primarily through grants to researchers at major U.S. medical institutions. NCC also disseminates free educational materials on cancer prevention, diagnosis, and treatment to the public via its website and publications.

irs program accomplishments · form 990 part iii · fy2024

What they reported doing

  1. #1 primary $1.46M
    PUBLIC AND PROFESSIONAL EDUCATION: THE ORGANIZATION PUBLISHES AND DISTRIBUTES LITERATURE AND PAMPHLETS PROMOTING SELF CARE TO THE PUBLIC. THE INFORMATION, MADE FREE TO ALL, ADDRESSES THE VARIOUS CANCER TYPES SUBJECT TO RESEARCH BY THE ORGANIZATION.NCC ALSO HAS A WEBSITE WWW.NATIONAL CANCER CENTER.ORG AND SOCIAL MEDIA AVAILABLE TO THE PUBLIC.
  2. #2 $5K
    HONORARIA PAID MEMBERS OF SCIENTIFIC ADVISORY BOARD. THE BOARD EVALUATES GRANT PROPOSALS AND PROVIDES INPUT ON RESEARCH PROJECTS FUNDED BY THE ORGANIZATION
named programs · 6 · from sources

What they call their work

Aggressive Cancer Research
Funds studies on high-mortality cancers such as pancreatic, lung, and liver cancer, with a focus on understanding core mechanisms and improving therapies to reduce toxicity and improve outcomes
Breast Cancer Project
Supports innovative research into genetic factors, immunotherapy, and improved detection and treatment methods for breast cancer, including funding at institutions like Duke University
Children’s Cancer Project
Funds pediatric cancer research, with a focus on neuroblastoma and early detection; supports education and prevention initiatives for childhood cancers
Fighting Childhood Leukemia
Targets research on molecular markers and therapies for childhood leukemia, the most common pediatric cancer, with grants to institutions like Dana-Farber Cancer Institute
NCC Project
Provides flexible fellowships for innovative research in areas beyond core programs, including brain tumors, melanoma, DNA repair, and immunotherapy
Prostate Cancer Project
Funds research into prostate cancer progression and treatment resistance, including studies on splicing mechanisms and therapeutic strategies
activities · 6 groups

What they do

  • Cancer Research Funding 2 activities
    • Funding targeted cancer research at academic institutions
      Awards grants to support specific research projects at leading institutions such as Dana-Farber Cancer Institute, Duke University, Johns Hopkins, University of Pittsburgh, Icahn School of Medicine at Mount Sinai, Children’s Hospital of Philadelphia, and others. Research areas include breast cancer genetics, colorectal cancer progression, aggressive cancers (pancreatic, lung, liver), intratumoral hypoxia, macrophage recruitment in triple-negative breast cancer, and residual cancer cells after CDK4/6 inhibition. Total disbursements exceed $9.74 million as of 2026.
    • Supporting research on aggressive cancers
      Funds research projects focused on aggressive cancers such as pancreatic, lung, and liver cancer through targeted grants, including a dedicated project established in 2015. This includes funding at Icahn School of Medicine at Mount Sinai and other institutions to identify novel therapeutics and understand mechanisms of progression and resistance.
  • Medical Research Funding 1 activity
    • Compensating scientific advisors for grant oversight
      Pays honoraria to members of its Scientific Advisory Board who evaluate grant proposals and provide input on funded research projects.
  • Cancer Awareness and Education Initiatives 1 activity
    • Disseminating cancer self-care education
      Publishes and distributes free literature and pamphlets on self-care related to cancer types under its research focus, and maintains a public website and social media presence to provide educational resources.
  • Psychoanalytic and Therapeutic Training Support 1 activity
    • Funding postdoctoral fellowships in cancer research
      Provides post-doctoral fellowships of $60,000 in the first year and $62,000 in the second year to early-career researchers under age 35 with limited post-doctoral experience, focusing on molecular genetics, cancer biology, tumor immunology, and pediatric cancers including childhood leukemia and neuroblastoma. In 2025, awarded $676,000 in fellowship grants to eleven scientists, and in 2026 funded $426,000 to support seven postdoctoral scientists.
  • Charity Event Organization 1 activity
    • Organizing fundraising events for research support
      Hosted the "Power of the Postdoc" event, which raised $45,000 to support postdoctoral fellowships in cancer research.
  • Uncategorized 1 activity
    • Requiring acknowledgment and reporting from grant recipients
      Requires acknowledgment of National Cancer Center support in scientific publications resulting from funded research and requests notification of such publications.
financials · form 990 · fy2024
revenue
Total revenue$3.61M
Contributions & grants$3.47M96%
Program service revenue$00%
Investment income$112K3%
Other revenue$24K
expenses
Total expenses$4.86M
Program expenses46%
Admin / overhead11%
Fundraising43%
Salaries & benefits$598K
Grants paid out$788K
Largest expense lineCompensation
balance sheet
Total assets$1.94M
Cash$580K
Investments$1.26M
Liabilities$1.36M
Net assets$575K
Liquid reserves4.5 mo
5 years on record · 2020–2024 · YoY revenue -17.2%
leadership · form 990 part vii · fy2024

Who runs it

paid leadership · 3
NameTitleHours/wkCompensation
Michelle Stack CEO 0 $165K
Regina English Consultant 40 $138K
Kris DiSanti Executive Director 40 $110K
board members · 5
  • Barry J Peek — President
  • Carolyn Sargent — Trustee
  • Jeremy Paul — Treasurer
  • Patrick Nasr — Trustee
  • Raymond L Forsythe — Vice President
relationships · 52

Who they work with

  • Aegis3 Fundraising Group Funder — Leading sponsor of the Power of the Postdoc event.
  • Arch Insurance Group Funder — Leading sponsor of the Power of the Postdoc event.
  • Beckman Research Institute at City of Hope Partner — Receives grant funding for research on KIFC1 as a biomarker in quadruple negative breast cancer.
  • Children's Hospital of Philadelphia Partner — Previously supported pediatric cancer research through a fellowship at Children's Hospital of Philadelphia.
  • City of Hope Partner — Currently funds cancer research at City of Hope in California.
  • City of Hope Partner — Funds cancer research at City of Hope in California.
  • Cleveland Clinic Partner — Receives grant funding for research on RNA splicing in prostate cancer.
  • Columbia University Partner — Currently funds cancer research at Columbia University.
  • Columbia University Partner — Funds cancer research at Columbia University.
  • Columbia University Partner — Receives grant funding for research on tumor microenvironment in pancreatic cancer subtypes.
  • Dana-Farber Cancer Institute Partner — Funds cancer research projects and postdoctoral fellowships at Dana-Farber Cancer Institute.
  • Dana-Farber Cancer Institute Partner — Funds research projects on colorectal cancer and childhood leukemia at Dana-Farber Cancer Institute.
  • Dana-Farber Cancer Institute Partner — Receives grant funding for research on Th1 cells in inflammation-associated colorectal cancer.
  • Dana-Farber Cancer Institute Partner — Receives grant funding for research on targeting residual cancer cells upon CDK4/6 inhibition.
  • Dana-Farber Cancer Institute Partner — Receives multiple grants for cancer research projects including mucosal melanoma, sarcoma, and prostate cancer.
  • Duke University Partner — Funds breast cancer research focusing on genetics, immunotherapy, and treatment improvements at Duke University.
  • Duke University Partner — Provides dedicated grant funding for breast cancer research at Duke University.
  • Duke University Partner — Received past grant funding for research on ALK4 loss and EMT regulation in pancreatic cancer.
  • Duke University Medical Center Partner — Receives grant funding from National Cancer Center for research into breast cancer genetics.
  • Harvard Medical School Partner — Receives grant funding for AI-based research on non-small cell lung cancer tumor microenvironment.
  • Harvard University Partner — Supports cancer research through grants to Harvard-affiliated institutions including Dana-Farber Cancer Institute.
  • Icahn School of Medicine at Mount Sinai Funder — Provides funding grant for the Aggressive Cancer Research project.
  • Icahn School of Medicine at Mount Sinai Partner — Funds aggressive cancer research at Icahn School of Medicine at Mount Sinai.
  • Icahn School of Medicine at Mount Sinai Partner — Provides grant funding for research on aggressive cancers at Icahn School of Medicine at Mount Sinai.
  • Johns Hopkins School of Medicine Partner — Receives renewed grant funding for research on intratumoral hypoxia and liver metastasis in breast cancer.
  • MIT Partner — Currently funds cancer research at MIT.
  • MIT Partner — Funds cancer research at Massachusetts Institute of Technology.
  • Massachusetts Institute of Technology Partner — Receives grant funding for research on stress-induced cancer cell migration.
  • NYU Grossman School of Medicine Partner — Receives grant funding for research on immune microenvironment in melanoma bone metastasis.
  • NYU School of Medicine Partner — Received past grant funding for research on CTCF mutations and nuclear architecture in cancer.
+ 22 more
strategies · 2

How they approach the work

Named approaches extracted from this org’s sources. Where others share an approach, follow it to see the full set of orgs running it.

  • Invest in early-career scientists through flexible postdoctoral fellowships
    methodology: flexible_fellowship_model
    By funding early-career postdoctoral researchers with flexible, high-risk research capacity, we accelerate transformative discoveries in cancer, because emerging scientists bring innovation and are more likely to pursue novel, high-impact pathways when freed from traditional funding constraints.
  • Target foundational cancer mechanisms to improve therapies
    methodology: targeting_core_cancer_mechanisms
    By focusing research investment on the core biological mechanisms of cancer—such as immunotherapy, epigenetics, and DNA repair—we generate more effective and less toxic treatments, because understanding root causes enables the development of targeted, transformative therapies.