irs program accomplishments · form 990 part iii · fy2024
What they reported doing
- #1 primary $488KSEVERE BRAIN INJURIES CAN OCCUR AT ANY STAGE OF LIFE. THEY CAN BE CAUSED BY EXTERNAL EVENTS LIKE A MOTOR VEHICLE ACCIDENT, SPORTS ACTIVITY, OR INTERNAL EVENTS LIKE A STROKE OR HEART ATTACK. THANKS TO IMPROVED TREATMENT, THE RATE OF PATIENTS WHO SURVIVE AFTER SUFFERING SEVERE BRAIN INJURIES IS INCREASING. WHILE SOME OF THESE PATIENTS REGAIN FULL CONSCIOUSNESS AFTER A TRANSIENT STATE OF COMA, OTHERS MAY DEVELOP MORE COMPLEX AND LASTING DISORDERS OF CONSCIOUSNESS AND BE BEHAVIORALLY UNRESPONSIVE EVEN THOUGH THEY OPEN THEIR EYES OR SHOW VERY MINIMAL, HARD TO DETECT, SIGNS OF CONSCIOUSNESS. THE IMPORTANCE OF ACCURACY IN SUCH A DIAGNOSIS CANNOT BE OVERSTATED: IT GUIDES TREATMENT ALLOCATION AND COULD MAKE THE DIFFERENCE BETWEEN AN END-OF-LIFE DECISION OR A SUSTAINED INTENSIVE CARE.
named programs · 2 · from sources
What they call their work
Consciousness Mapping
Joint research initiative between Paris Brain Institute and Columbia University to develop a multimodal, machine learning–based diagnostic tool for patients with disorders of consciousness, improving accuracy in diagnosis and enabling personalized treatment strategies
New Therapeutic Strategies for Glioblastoma
Four-year collaborative project between Paris Brain Institute and Harvard Medical School focused on targeting tumor plasticity and enhancing immunotherapy efficacy in glioblastoma, the most aggressive form of brain cancer
activities · 6 groups
What they do
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Neurological Disorder Research & Rehabilitation 2 activities
- Developing diagnostic tools for disorders of consciousnessDevelops a multimodal, personalized diagnostic tool for disorders of consciousness using machine learning, informed by clinical data collected from patients in France and the United States using physiology, electrophysiology, and neuroimaging techniques.
- Researching remyelination in multiple sclerosisConducts research to identify molecular and cellular factors influencing remyelination in multiple sclerosis, aiming to enable personalized treatments.
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International Student Recruitment & Academic Partnerships 1 activity
- Building international research collaborations with U.S. institutionsSupports the international development of Paris Brain Institute and enhances collaborations with American scientists and institutions by creating joint research teams.
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Biomedical Research and Innovation 1 activity
- Conducting fundamental research on glioblastomaConducts translational and fundamental research on glioblastoma using 2D and 3D imaging, genomics, preclinical modeling, and drug development to advance understanding and treatment approaches.
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Genetic and Neurological Disease Research Funding 1 activity
- Funding neuroscience research on disorders of consciousnessSupports neuroscience research focused on disorders of consciousness following severe brain injuries, including those caused by trauma, stroke, or cardiac events. The organization spent $488,098 on this research programming in 2024.
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Medical Research Funding 1 activity
- Funding personalized care protocols for traumatic brain injuryFinances a four-year transatlantic research project to develop personalized care protocols for traumatic brain injury patients, led by Dr. Jacobo Sitt of Paris Brain Institute and Dr. Jan Claassen of Columbia University.
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Cancer Research Funding 1 activity
- Funding transatlantic research on glioblastoma therapiesFinances a four-year transatlantic research project to develop new therapies for glioblastomas, led by Dr. Mehdi Touat of Paris Brain Institute and Dr. Keith Ligon of Harvard Medical School.
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financials · form 990 · fy2024
revenue
Total revenue$1.99M
Contributions & grants$1.53M77%
Program service revenue$00%
Investment income$1010%
Other revenue$456K
expenses
Total expenses$1.44M
Program expenses92%
Admin / overhead3%
Fundraising6%
Salaries & benefits$22K
Grants paid out$267K
Largest expense lineProfessional Fees
balance sheet
Total assets$2.08M
Cash$1.07M
Investments$20K
Liabilities$982K
Net assets$1.10M
Liquid reserves9.1 mo
2 years on record · 2023–2024 · YoY revenue +228.1%
leadership · form 990 part vii · fy2024
Who runs it
paid leadership · 1
| Name | Title | Hours/wk | Compensation |
|---|---|---|---|
| MARIANNE SCORDEL | EXECUTIVE OFFICER FROM 11/2024 | 40 | $20K |
board members · 6
- HENRY GAZAY — DIRECTOR
- JEAN TODT — DIRECTOR
- MARTINE ASSOULINE — CHAIR AND PRESIDENT
- MATHILDE COSTE — TREASURER
- RICHARD HSIAO — DIRECTOR
- ZOFIA MORENO — SECRETARY
relationships · 14
Who they work with
- Columbia University Partner — Collaborates with Paris Brain Institute on a 4-year research project to develop a personalized diagnostic tool for disorders of consciousness.
- Columbia University Partner — Collaborates with Paris Brain Institute on a four-year research project to create personalized care protocols for traumatic brain injury patients.
- French Consulate in New York Partner — Hosted the annual dinner of Paris Brain Institute America in October 2024.
- Harvard Medical School Partner — Collaborates with Paris Brain Institute on a four-year research project to develop new therapies for glioblastomas.
- Harvard Medical School Partner — Collaborates with Paris Brain Institute on research to identify treatment vulnerabilities in glioblastoma.
- Lycée Français de New York Partner — Hosted a public interview event featuring Bassem Hassan and NYU's Claude Desplan.
- Lycée Français de New York (LFNY) Partner — Hosted a conference with Dr. Bassem Hassan in New York, indicating institutional partnership for public scientific outreach.
- New York University Partner — Collaborates with NYU faculty, including Claude Desplan, for scientific events and discussions.
- New York University (NYU) Partner — Hosted a scientific conversation featuring a Paris Brain Institute researcher and a NYU professor, indicating academic collaboration.
- Paris Brain Institute Partner — Collaborates with and promotes research discoveries from Paris Brain Institute in fundraising and public outreach activities.
- Paris Brain Institute Partner — Hosts Violetta Zujovic's research team and supports her work on myelin plasticity and regeneration.
- Paris Brain Institute Partner — Primary beneficiary and research counterpart; Paris Brain Institute America raises funds and builds collaborations to support its work.
- TIME Partner — Featured Alice Park, TIME's Senior Health Correspondent, as moderator of a scientific interview event.
- TIME Magazine Partner — Featured Alice Park, Senior Health Correspondent at TIME, as moderator for a scientific conversation event.
strategies · 4
How they approach the work
Named approaches extracted from this org’s sources. Where others share an approach, follow it to see the full set of orgs running it.
- Personalized Medicine through Molecular Determinantsmethodology: personalized-medicineBy identifying molecular and cellular mechanisms underlying remyelination, the organization enables personalized treatment strategies for multiple sclerosis, because individual biological variation determines therapeutic response.
- Precision Diagnosis in Neurologymethodology: precision-diagnosis-in-neurologyBy leveraging advanced diagnostic tools and accurate assessment of disorders of consciousness, the organization aims to guide appropriate treatment decisions and prevent premature end-of-life decisions, because precise diagnosis is foundational to ethical and effective patient care.
- Targeting Tumor Plasticity and Microenvironment in Glioblastomamethodology: tumor_plasticity_targetingBy focusing on tumor cell plasticity, heterogeneity, and immunotherapy resistance mechanisms within the tumor microenvironment, the organization seeks to overcome treatment resistance in glioblastoma, because these biological factors are key drivers of therapeutic failure.
- Transatlantic Collaborative Research Modelmethodology: transatlantic_collaborative_researchBy uniting scientists, clinicians, entrepreneurs, and donors across the U.S. and France, the organization accelerates brain disease research and translation to patient benefit, because cross-border, multidisciplinary collaboration integrates complementary expertise and resources more effectively than isolated efforts.