COMMON MAPS
Map version new-york activity top-down
Main site Contact
Menu
↑ parent activity group ·
research dossier

HAUPTMAN-WOODWARD MEDICAL RESEARCH INSTITUTE INC

Buffalo, NY · EIN 160807558 · Form 990 · FY2023 · NTEE H20Z · Medical Research · Large ($10M-$50M) · hwi.buffalo.edu
revenue
$11.0M
expenses
$10.5M
net assets
$22.5M
employees
37
volunteers
21
program ratio
86%
mission · from form 990

Guided by its motto, CURE-OSITY, the Hauptman-Woodward Medical Research Institute (HWI) creates novel strategies and technologies to promote the understanding, prevention, and treatment of many human diseases. HWI scientists conduct basic, fundamental research that will provide for effective therapeutic approaches far into the future. Often our research includes identifying proteins involved in disease which allows treatments to be more effective by targeting those proteins. Examples of current projects include breast cancer, prostate cancer, multiple myeloma, studying the effect of gravity on cells, and biological cell structure determination for nearly all disease through the use of hard X-ray free electron lasers (XFELs) and high-throughput crystallization.

profile · synthesized from sources

Hauptman-Woodward Medical Research Institute (HWI) conducts fundamental biomedical research focused on understanding the molecular basis of human diseases. The institute develops and applies advanced technologies such as X-ray crystallography, cryo-electron microscopy, and high-throughput screening to identify disease-related proteins and support future therapeutic development. Its research services are used by academic, government, and non-profit scientists nationwide.

irs program accomplishments · form 990 part iii · fy2023

What they reported doing

  1. #1 primary $3.86M
    IMCA-CAT provided an outstanding support environment for macro-molecular crystallography by developing and operating an efficient, reliable , high-throughput facility at which both confidential and proprietary equipment can be readily and easily accommodated.
  2. #2 $1.19M
    The National HTX Center aims to implement a modern internet interface for users of the High-Throughput Crystallization Screening Center to interact with the images of their crystallization screening experiments. A further goal is to begin development of software to enable automatic image analysis and classification.
named programs · 4 · from sources

What they call their work

Cryo-Electron Microscopy Center
Provides single-particle cryo-EM and microcrystal electron diffraction services to support 3D structure determination of biological macromolecules for research institutions and industry
IMCA-CAT
High-throughput macromolecular crystallography facility supporting structural biology research with advanced synchrotron-based instrumentation and data collection capabilities
National Crystallization Center
NIH-supported facility providing high-throughput protein crystallization services to academic, government, and non-profit researchers for structural biology studies
National HTX Center
Develops software and web-based tools for remote access and automated analysis of high-throughput crystallization screening data
activities · 1 group

What they do

  • Biomedical Research and Innovation 3 activities
    • Cryo-electron microscopy services
      Provides single-particle and microcrystal electron diffraction services through its Cryo-Electron Microscopy Center to academic, government, non-profit, and industry research organizations.
    • Digital infrastructure for crystallography data access and analysis
      Implements a modern internet interface that allows users to access images from high-throughput crystallization screening experiments and develops software for automated image analysis and classification to support structural biology research.
    • High-throughput macromolecular crystallography
      Develops and operates a high-throughput facility for macromolecular crystallography that supports structural biology research and accommodates confidential and proprietary equipment. Provides protein crystallization services to academic, government, and non-profit research institutes.
financials · form 990 · fy2023
revenue
Total revenue$11.03M
Contributions & grants$3.57M32%
Program service revenue$4.64M42%
Investment income$2.30M21%
Other revenue$511K
expenses
Total expenses$10.45M
Program expenses86%
Admin / overhead13%
Fundraising1%
Salaries & benefits$2.80M
Grants paid out$0
Largest expense lineCompensation
balance sheet
Total assets$27.56M
Cash$27K
Investments$13.99M
Liabilities$5.01M
Net assets$22.55M
Liquid reserves16.1 mo
5 years on record · 2019–2023 · YoY revenue +26.9%
leadership · form 990 part vii · fy2023

Who runs it

paid leadership · 10
NameTitleHours/wkCompensation
Edward Snell Chief Scientific Officer 38 $255K
Lisa Keefe VP 38 $240K
Anne Kent Chief Financial Officer 38 $180K
Devrim Acehan Cryo-EM Director 38 $167K
Daniel Gewirth Principal Research Scientist 38 $158K
John Muir Software Developer 38 $154K
Blanca Carbajal Business Development Director 38 $139K
Aviv Paz Principal Investigator 38 $132K
Sarah Bowman Board Member/Associate Investigator 38 $123K
Christopher Greene Interim CEO 1 $120K
board members · 15
  • Andrei Gudkov — Board Member
  • Artem Evdokimov — Board Member
  • Brenda McDuffie — Board Member
  • Christina Arthurs — Board Member
  • Dan Magnuszewski — Board Member
  • EJ Burke — Board Member
  • Franca Trincia — Board Member
  • Frank Ewing — Board Member
  • Jeffrey Renzoni — Board Member
  • Jill Bond — Board Member/Secretary
  • LaVonne Ansari — Board Member
  • Michele Heffernan — Board Member
  • Nena Rich — Board Member
  • Philip Nobel — Board Member
  • Sam Russo — Board Member/Chairperson of the Board
relationships · 2

Who they work with

  • IMCA-CAT Partner — Collaborates on providing a high-throughput facility for macro-molecular crystallography.
  • National Institutes of Health Government — Primary funder of the National Crystallization Center.
strategies · 3

How they approach the work

Named approaches extracted from this org’s sources. Where others share an approach, follow it to see the full set of orgs running it.

  • Basic and Fundamental Research as Foundation for Therapeutics
    methodology: basic_research_foundation
    By conducting basic, fundamental research, we enable the long-term development of effective therapeutic approaches, because foundational scientific discoveries create the necessary knowledge base for future applied innovations and medical breakthroughs.
  • Shared Research Infrastructure Model
    methodology: shared_research_infrastructure
    By providing external research organizations access to advanced, specialized facilities and services (e.g., protein crystallization and cryo-electron microscopy), we accelerate structural biology research across diverse scientific communities, because centralized, expert-maintained infrastructure reduces duplication, lowers barriers to high-resolution analysis, and enables research that would otherwise be infeasible for individual institutions.
  • Targeted Protein Research for Therapeutics
    methodology: targeted_protein_research
    By identifying disease-related proteins, we enable the development of more effective, targeted therapeutic approaches, because understanding the molecular targets of disease allows for precise intervention and drug design.